A target is a cellular structure that is involved in a molecular-level of a specific disease and can be modulated by a therpeutic. It could be an enzyme, receptor, nucleic acid, hormone, ion channel, membrane proteins, etc. There are several ways to Identify a ‘druggable’ target implicated in the disease process or generation of symptoms. Here you will find information about methods, tools and strategies such as: in silico screening, next generation screening, phenotypic screening or structural analysis”.

Once identified, the next step is to demonstrate that drug effects on the target can provide a therapeutic benefit with an acceptable safety window through a multifunctional process using validation techniques in disease models in vitro tools and vivo models.