This site provides a central resource for the European fly community. It contains useful information about the European Drosophila Board, which supports community initiatives and oversees the organisation of the biennial European Drosophila Research Conference.
View this resource Bookmark this resourceAnimal Model
Animal models for metabolic, neuromuscular and ophthalmological rare diseases
Published by Macmillan Publishers Limited
Animal ModelFeline ModelInfrafrontierMouse ModelNeuromuscular DiseaseOphtalmological Diseasethe article provides a compilation of mammalian animal
models for metabolic, neuromuscular and ophthalmological orphan-designated conditions
based on information gathered by the EMA’s Committee for Orphan Medicinal Products (COMP). It is discussed the predictive value of the models and their advantages and limitations with the aim of highlighting those that are appropriate for the preclinical evaluation of novel
therapies, thereby facilitating further drug development for rare diseases.
KNOCKOUTS MODEL THE 100
BEST-SELLING DRUGS — WILL THEY
MODEL THE NEXT 100?
Published by Nature
Knock-Out Mouse Modelthis article is a retrospective evaluation of the knockout phenotypes for the targets of the 100 best-selling drugs indicates that these phenotypes correlate well with known drug efficacy, illuminating a productive path forward for discovering future drug targets
View this resource Bookmark this resourcelist ofresearch publications of the Infrafrontier Research infrastructures
View this resource Bookmark this resourceA Contract Research Organization that uses zebrafish to carry out a number of experimental services focused on analyzing the Safety, efficacy and biomedical relevance of new compounds. In the website it can be found resources, data bases and research publications.
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Nonhuman Primate Models in the Genomic Era: A Paradigm Shift
Published by ILAR J.
Non-Human Primate ModelThis article describes the genetic and genomic revolution thath is changing the paradigm of the nonhuman primates as a disease model and the new mandates on how nonhuman primates are used in biomedical research.
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Mammalian animal models for Duchenne muscular dystrophy
Published by Elsevier B.V
Duchenne Muscular DystrophyMammalian Animal ModelThis review compares the currently used mammalian animal models for DMD with the aim of selecting and recommending the most appropriate ones for preclinical efficacy testing of new therapeutic strategies.
View this resource Bookmark this resourceThe CCAC guidelines: Nonhuman primates provides information for investigators, animal care committees, facility managers, veterinarians and animal care staff to help facilitate improvement in both the care given to nonhuman primates and the manner in which experimental procedures are carried out
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NC3Rs Guidelines: Non-human primate, accommodation, care and use
Published by National Centre for the Replacement, Refinement and Reduction of Animals in Research
NHPNonhuman primatesThis Guideline is created by the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) which supports the principles
of the 3Rs and provides the high standards of accommodation and care for animals used in research.
A guide for the laboratory use of zebrafish Danio (Brachydanio) rerio
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