The Cellosaurus is a knowledge resource on cell lines. It attempts to describe all cell lines used in biomedical research, including:
Immortalized cell lines
Naturally immortal cell lines (example: stem cell lines)
Finite life cell lines when those are distributed and used widely
Vertebrate cell line with an emphasis on human, mouse and rat cell lines
Invertebrate (insects and ticks) cell lines
Provided by Human Pluripotent Stem Cell Registry (hPSCreg)
Benefits of the global registry for human pluripotent stem cell lines hPSCreg are
– increased visibility of your hPSC line within the regenerative medicine community worldwide
– assignment of a unique cell line reference code to allow traceability in published papers and across federated on-line resources
– obtain hPSC certificates to fulfill ethical provenance requirements for EC-funded research projects
– recognition of source biomaterial ethical provenance and other cell line characteristics
PhenomeCentral is a repository for secure data sharing targeted at clinicians and scientists working in the rare disorder community. We encourage global scientific collaboration while respecting the privacy of patients profiled in this centralized database. PhenomeCentral uses state-of-the-art algorithms to match cases on phenotype and genotype. You can find similar cases even if there are no phenotypes in common, because terms are matched semantically rather than using textual similarity. You can enter candidate genes or let the Exomiser automatically prioritize genes from exome sequencing data.
Visit website
The purpose of CellML is to store and exchange computer-based mathematical models. CellML allows scientists to share models even if they are using different modelling tools. It also enables them to reuse components from one model in another, thus accelerating model development
Visit websiteProvided by EUROPEAN RESEARCH INFRASTRUCTURE ON HIGHLY PATHOGENIC AGENTS (ERINHA)
The services offered by ERINHA includea.o.
• Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens. In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates). In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities.
Genethon has platforms available which are capable of generating and collecting all the preclinical data which make it possible to evaluate efficacy, toxicity and adverse effects of a gene therapy product, including functional exploration, imaging, histology, cytology as well as an animal experimentation center
Visit website
The IFB’s services have two main objectives: the deployment of a high-performance bioinformatics service optimized for the needs of the life sciences communities (university laboratories and industries) and the development of innovative bioinformatics resources to address strategic challenges in health, environment and agriculture. As such, IFB provides support, account opening, software and database installation, website and virtual machine hosting, software/database/ information system development and bio-data analysis
Visit website
RD-Connect has developed several bioinformatic tools to help researchers analyse omics data and identify targets for potential therapies. These include variant analysis and annotation tools as well as therapeutic prediction tools and gene-drug interaction resources, many of which are integrated in the Genome-Phenome Analysis Platform. RD-Connect Genome-Phenome Analysis Platform is a userfriendly tool that lets researchers and clinicians analyse DNA sequencing data and link them to clinical information (i.e. description of symptoms of the patients). This helps to understand how genes determine the disease symptoms and their severity, make accurate genetic diagnosis and design better treatment.
Visit websiteThe SEFALer platform is a pioneering network structure seeking to provide a comprehensive service in all phases of phenotyping animal models of rare diseases. It is structured through cooperation between services provided by CIBERER groups through different institutions.Actvities include:
1. Characterisation of animal models of human rare diseases.
*Secondary functional phenotyping in the following contexts:
– Platforms for phenotyping transgenic mice.
– Pharmacology and toxicology.
– Degeneration and regeneration studies.
– Ageing studies.
– Characterisation of experimental models forming part of behavioural, surgical studies, etc. Phenotypic selection of reproducers for stabling.
*Morphological phenotyping.
2.CIBERER database: models available, genic expression and phenotype.
3. Technical-scientific advice.
4. Training
The Tools Platform helps communities find, register and benchmark software tools. These tools help researchers access, analyse and integrate biological data, and so drive scientific discovery across the life sciences.
We maintain information standards for these tools, and produce, adopt and promote best practices for their development. We also:
*connect tools and data services
*link tools to training materials
*make it easy to download, deploy, and benchmark tools for performance
*put tools in the context of the common workflows in bioinformatics, including container technologies and Galaxy.
