Services offered by Instruct include
Computational Services for Structural Biology: Bioinformatics Tools, Integrative Modelling, Crystallography, Electron Microscopy, NMR
More information about our current technology offering can be found at https://instruct-eric.eu/platform-catalogue
Provided by CCRI (Children's Cancer Research Institute)
* Bioinformatics: The bioinformatics team provides advice and support for CCRI researchers with regard to analysis, integration and interpretation of large scale genomics datasets. We maintain and run computational pipelines for processing raw next-generation sequencing (NGS) data and data quality checks for all genomics data held within the CCRI/St.Anna Children´s Hospital. We are also performing high quality data analyses in close collaboration with CCRI/St.Anna Children´s Hospital researchers.
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* Zebrafish platform Austria for Preclinical drug Screening (ZANDR) is a unique platform to phenotypically screen small compounds on zebrafish models of human diseases.
Zebrafish and in particular zebrafish larvae is a well suited vertebrate model system to investigate various human diseases and to perform cost-effective screens for small molecules with therapeutic potential (1). Funded by FFG, we have established a zebrafish-optimized and automated screening platform, which is open to the scientific community. Please contact us, if you are interested in collaboration: www.zandr-ccri.at
The Cellosaurus is a knowledge resource on cell lines. It attempts to describe all cell lines used in biomedical research, including:
Immortalized cell lines
Naturally immortal cell lines (example: stem cell lines)
Finite life cell lines when those are distributed and used widely
Vertebrate cell line with an emphasis on human, mouse and rat cell lines
Invertebrate (insects and ticks) cell lines
Provided by Human Pluripotent Stem Cell Registry (hPSCreg)
Benefits of the global registry for human pluripotent stem cell lines hPSCreg are
– increased visibility of your hPSC line within the regenerative medicine community worldwide
– assignment of a unique cell line reference code to allow traceability in published papers and across federated on-line resources
– obtain hPSC certificates to fulfill ethical provenance requirements for EC-funded research projects
– recognition of source biomaterial ethical provenance and other cell line characteristics
PhenomeCentral is a repository for secure data sharing targeted at clinicians and scientists working in the rare disorder community. We encourage global scientific collaboration while respecting the privacy of patients profiled in this centralized database. PhenomeCentral uses state-of-the-art algorithms to match cases on phenotype and genotype. You can find similar cases even if there are no phenotypes in common, because terms are matched semantically rather than using textual similarity. You can enter candidate genes or let the Exomiser automatically prioritize genes from exome sequencing data.
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The purpose of CellML is to store and exchange computer-based mathematical models. CellML allows scientists to share models even if they are using different modelling tools. It also enables them to reuse components from one model in another, thus accelerating model development
Visit websiteProvided by EUROPEAN RESEARCH INFRASTRUCTURE ON HIGHLY PATHOGENIC AGENTS (ERINHA)
The services offered by ERINHA includea.o.
• Access to state of art European high containment (BSL4 & BSL3) and complementary facilities to advance research on high-consequence pathogens. In-vivo testing with a variety of animal models (including small rodents, ferrets, and non-human primates). In-vitro experiments using highly pathogenic agents with both in-person and remote access possibilities.
Genethon has platforms available which are capable of generating and collecting all the preclinical data which make it possible to evaluate efficacy, toxicity and adverse effects of a gene therapy product, including functional exploration, imaging, histology, cytology as well as an animal experimentation center
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The IFB’s services have two main objectives: the deployment of a high-performance bioinformatics service optimized for the needs of the life sciences communities (university laboratories and industries) and the development of innovative bioinformatics resources to address strategic challenges in health, environment and agriculture. As such, IFB provides support, account opening, software and database installation, website and virtual machine hosting, software/database/ information system development and bio-data analysis
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