Research and Drug Development

The information and resources in this section can help you navigate in the Research and Drug Development area to identify issues classified for:
Disease models,
Disease/Translational resources,
Drug Discovery,
Clinical Development,

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Tissue Chip for Drug Screening program and Consortium

Published by IRDiRC

BiomarkerDrug DiscoveryDrug Screening ProgrammeHigh Throughput ScreeningLibraryNCATSResearch and Drug DevelopmentTissue Chip

NCATS, in collaboration with other NIH Institutes and Centers and the Food and Drug Administration (FDA), is leading the Tissue Chip for Drug Screening program to develop human tissue chips that accurately model the structure and function of human organs — such as the lungs, liver and heart — to help predict drug Safety in humans more rapidly and effectively

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Core Outcome Measures in Effectiveness Trials

Published by IRDiRC

Clinical DevelopmentClinical Trial DesignEffectiveness TrialEndpoint COMETOutcome MeasureResearch and Drug Development

The COMET (Core Outcome Measures in Effectiveness Trials) Initiative brings together people interested in the development and application of agreed standardised sets of outcomes, known as ‘core outcome sets’ (COS). These sets represent the minimum that should be measured and reported in all clinical trials of a specific condition, and are also suitable for use in clinical audit or research other than randomised trials.

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