This review will look at key preclinical stages of the drug discovery process, from initial target identification and validation, through assay development, high throughput screening, Hit Identification, Lead Optimization and finally the selection of a candidate molecule for clinical development.
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Principles of Early Drug Discovery
Published by Br J Pharmacol.
Drug Development StageHit IdentificationLead OptimisationPrinciple of Early Drug DiscoveryTarget Identification
