Disease Model

In this section you will have the opportunity to explore cellular models:
patient-derived immortalized cell lines, and animal models
Patient-derived induced pluripotent stem cell (iPSCs)
Organoid
You can also find information regarding animal models:
Zebra Fish
Fruit fly
Mouse
Rat
Non-human primates

  1. Showing 43 results for:
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  3. Disease Model
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In Silico Model

Published by Animal Biotechnology

In silico

This article is a review of the main concepts about In silico modeling of diseases. Examples and applications of In silico modeling for some important categories of diseases (such as for cancers, infectious diseases, and neuronal diseases) are also given.

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In Silico Model in Toxicology and Risk Assessment

Published by Frontiers Media

In silicophysiologically-based kinetic and dynamic modelQSAR model

This article aims to address the latest developments in the area of In silico modelling and New approach methodologies (NAMs) including physiologically-based kinetic and dynamic (PBK-D) model, In silico model for the prediction of toxicological such as QSAR model and machine learning algorithms, the use of quantitative adverse outcome pathways for hazard characterisation of chemicals to cite but a few

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Animal models for metabolic, neuromuscular and ophthalmological rare diseases

Published by Macmillan Publishers Limited

Animal ModelFeline ModelInfrafrontierMouse ModelNeuromuscular DiseaseOphtalmological Disease

the article provides a compilation of mammalian animal
models for metabolic, neuromuscular and ophthalmological orphan-designated conditions
based on information gathered by the EMA’s Committee for Orphan Medicinal Products (COMP). It is discussed the predictive value of the models and their advantages and limitations with the aim of highlighting those that are appropriate for the preclinical evaluation of novel
therapies, thereby facilitating further drug development for rare diseases.

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KNOCKOUTS MODEL THE 100 BEST-SELLING DRUGS — WILL THEY MODEL THE NEXT 100?

Published by Nature

Knock-Out Mouse Model

this article is a retrospective evaluation of the knockout phenotypes for the targets of the 100 best-selling drugs indicates that these phenotypes correlate well with known drug efficacy, illuminating a productive path forward for discovering future drug targets

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Nonhuman Primate Models in the Genomic Era: A Paradigm Shift

Published by ILAR J.

Non-Human Primate Model

This article describes the genetic and genomic revolution thath is changing the paradigm of the nonhuman primates as a disease model and the new mandates on how nonhuman primates are used in biomedical research.

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